Adding some certain compound to certain chemical reactions, such as: 6065-82-3, name is Ethyl diethoxyacetate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6065-82-3. 6065-82-3
I) diethoxyacetic acid To a solution of ethyl diethoxyacetate (5.00 g) in ethanol (20 mL) was added 1M aqueous sodium hydroxide solution (60 mL). The reaction mixture was stirred at room temperature for 2 hr, and ethanol was evaporated under reduced pressure. An aqueous solution of the residue was washed with diethyl ether, and adjusted to pH 3-4 with 2M hydrochloric acid, and extracted with ethyl acetate. The extract was washed with saturated brine, and dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give the title compound (3.00 g). 1H NMR (400 MHz, CDCl3) delta 1.27 (6H, t, J=7.2 Hz), 3.64-3.77 (4H, m), 4.96 (1H, s), 8.91 (1H, br s).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Ethyl diethoxyacetate.
Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; Kawasaki, Masanori; Mikami, Satoshi; Nakamura, Shinji; Negoro, Nobuyuki; Ikeda, Shuhei; Nomura, Izumi; Ashizawa, Tomoko; Imaeda, Toshihiro; Seto, Masaki; Sasaki, Shigekazu; Marui, Shogo; Taniguchi, Takahiko; (130 pag.)US2016/159808; (2016); A1;,
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